Pathways to Recovery: Psychosis and SchizophreniaPsychosis, a condition marked by a loss of touch with reality, is distressing for those who experience it and their loved ones. If left untreated, psychosis can have serious impacts on people's lives. But the good news is there's hope. In this episode, we talk with Dr. Robert Heinssen, a leader in the development and adoption of coordinated specialty care for treating psychosis. We learn about the signs and symptoms of psychosis, discuss coordinated specialty care, and explore how NIMH research in psychosis and schizophrenia fundamentally changed the health care landscape.

Practice-Based Suicide Prevention Centers MeetingIn 2020, the National Institute of Mental Health (NIMH) launched the Practice-Based Suicide Prevention Research Centers, modeled after the Advanced Laboratories for Accelerating the Reach and Impact of Treatments for Youth and Adults with Mental Illness (ALACRITY) Research Center program. The Practice-Based Suicide Prevention Research Centers are integrated, transdisciplinary research programs aimed at developing, refining, and testing effective and scalable approaches for reducing suicide rates in the United States. The centers support research that could not be achieved using standard research project grant mechanisms. The goal of this meeting on April 10, 2024, was to bring together the directors of the seven centers to provide an overview of each of the projects and help each other achieve their common mission. Learn more about this meeting at: https://www.nimh.nih.gov/news/events/2024/practice-based-suicide-prevention-centers-meeting

Facebook Live: Brain Stimulation TherapiesIn recognition of National Mental Health Awareness Month in May, the National Institute of Mental Health (NIMH) hosted a Facebook Live event on brain stimulation therapies on May 1, 2024. The event featured NIMH expert Sarah H. Lisanby, M.D., Director of the Noninvasive Neuromodulation Unit in the Experimental Therapeutics and Pathophysiology Branch and Director of the NIMH Division of Translational Research. Brain stimulation therapies can help people with certain mental disorders who have not responded to other treatments. During the event, Dr. Lisanby described common types of brain stimulation therapies and why they are used, dispelled misconceptions, and highlighted NIMH-supported research in this area.

Day 2: From Single-Cell Genomics to Brain Function and Disorders—Data Integration and AnnotationA vast amount of single-cell genomic profiling data has been generated to date from human and other mammalian brains by the National Institutes of Health's (NIH) Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative - Cell Census Network (BICCN) and the Cell Atlas Network (BICAN) and the broad research community to characterize brain cell types and states across lifespan and diseases. These information-rich data represent a tremendous research advancement, which engenders new and essential opportunities for data analysis, integration, and annotation. This workshop from January 16-18, 2024, featured targeted and coordinated presentations, panel discussions, and demonstrations with the following goals: -Foster the development of data standards for the integration and annotation of single-cell genomics data. -Systemize and automate the process of data to information to knowledge and develop pipelines where feasible -Shed new insights on brain cell functional studies by using cell atlasing data and cell type-specific targeting tools. -Develop strategies with brain disease research communities to maximally leverage BICCN/BICAN data. -Develop a community roadmap for the analysis and annotation of single-cell data. The overarching BRAIN Initiative Cell Atlasing Program goal is to build reference brain cell atlases that will be widely used throughout the research community, providing a molecular and anatomical foundational framework for the study of brain function and disease. Learn more: https://www.nimh.nih.gov/news/events/2024/the-brain-initiativer-cell-atlas-workshop-from-single-cell-genomics-to-brain-function-and-disorders-data-integration-and-annotation

Day 3: From Single-Cell Genomics to Brain Function and Disorders—Data Integration and AnnotationA vast amount of single-cell genomic profiling data has been generated to date from human and other mammalian brains by the National Institutes of Health's (NIH) Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative - Cell Census Network (BICCN) and the Cell Atlas Network (BICAN) and the broad research community to characterize brain cell types and states across lifespan and diseases. These information-rich data represent a tremendous research advancement, which engenders new and essential opportunities for data analysis, integration, and annotation. This workshop from January 16-18, 2024, featured targeted and coordinated presentations, panel discussions, and demonstrations with the following goals: -Foster the development of data standards for the integration and annotation of single-cell genomics data. -Systemize and automate the process of data to information to knowledge and develop pipelines where feasible -Shed new insights on brain cell functional studies by using cell atlasing data and cell type-specific targeting tools. -Develop strategies with brain disease research communities to maximally leverage BICCN/BICAN data. -Develop a community roadmap for the analysis and annotation of single-cell data. The overarching BRAIN Initiative Cell Atlasing Program goal is to build reference brain cell atlases that will be widely used throughout the research community, providing a molecular and anatomical foundational framework for the study of brain function and disease. Learn more: https://www.nimh.nih.gov/news/events/2024/the-brain-initiativer-cell-atlas-workshop-from-single-cell-genomics-to-brain-function-and-disorders-data-integration-and-annotation